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#11581 |
Blu-ray Jedi
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My employer is expanding their workforce to keep up with the new outdoor dining demand, surprised I wasn't 1 of the 3 dishwashers they picked. The 2 long-time employees I understand but not sure why that uber slow new guy was picked over me, they're probably going to regret that decision on the nights they're there till like 12 AM when they should be out closer till 10 LOL.
Small comfort is at least it's more time away from a job I hate, with hopefully another stimulus check and more aid from my school coming. Last edited by Batman1980; 07-19-2020 at 10:00 PM. |
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#11582 | ||
Blu-ray Duke
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https://www.reddit.com/r/astoria/com...th_ave_228_am/ Good times. |
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#11583 | ||
Retired Hollywood Insider
Apr 2007
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![]() ![]() nevertheless, I’m willing to learn about places like Astoria, all serves a purpose ![]() P.S. well, sports figures and ‘Sam’ ![]() Last edited by Penton-Man; 07-20-2020 at 12:14 AM. Reason: added a P.S. |
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Thanks given by: | IndyMLVC (07-20-2020) |
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#11584 |
Retired Hollywood Insider
Apr 2007
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welp, this study on age-related transmissibility should cause some consideration –
https://www.forbes.com/sites/rachels.../#773bc843fa7a |
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#11585 | |
Blu-ray Champion
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#11587 |
Blu-ray Ninja
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CNBC - Coronavirus vaccine from Oxford and AstraZeneca shows positive response in early trial
Early results of the 1,000 person trial of the Oxford/Astra Zeneca vaccine released this morning. No major side effects, neutralizing antibodies after 28 days, plus t-cells. Human trials in the USA with this vaccine are expected in the next few weeks. edit: BBC article woops that should have specified that neutralizing antibodies peak after 28 days, then decline; t-cells peak after 14 days, then decline... that's not particularly promising. The study wasn't run long enough to see how much they drop off. This is more disappointing than I thought. Last edited by ctujackbauer; 07-20-2020 at 02:34 PM. |
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#11589 | |
Blu-ray Prince
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#11590 |
Retired Hollywood Insider
Apr 2007
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#11591 | |
Retired Hollywood Insider
Apr 2007
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SARS-COV-2 NEUTRALIZATION RESPONSES No participant had detectable PsVNA responses before vaccination. After the first vaccination, PsVNA responses were detected in less than half the participants, and a dose effect was seen (50% inhibitory dilution [ID50]: Figure 2C, Fig. S8, and Table 2; 80% inhibitory dilution [ID80]: Fig. S2 and Table S6). However, after the second vaccination, PsVNA responses were identified in serum samples from all participants. The lowest responses were in the 25-μg dose group, with a geometric mean ID50 of 112.3 (95% CI, 71.2 to 177.1) at day 43; the higher responses in the 100-μg and 250-μg groups were similar in magnitude (geometric mean ID50, 343.8 [95% CI, 261.2 to 452.7] and 332.2 [95% CI, 266.3 to 414.5], respectively, at day 43). These responses were similar to values in the upper half of the distribution of values for convalescent serum specimens. Before vaccination, no participant had detectable 80% live-virus neutralization at the highest serum concentration tested (1:8 dilution) in the PRNT assay. At day 43, wild-type virus–neutralizing activity capable of reducing SARS-CoV-2 infectivity by 80% or more (PRNT80) was detected in all participants, with geometric mean PRNT80responses of 339.7 (95% CI, 184.0 to 627.1) in the 25-μg group and 654.3 (95% CI, 460.1 to 930.5) in the 100-μg group (Figure 2D). Neutralizing PRNT80 average responses were generally at or above the values of the three convalescent serum specimens tested in this assay. Good agreement was noted within and between the values from binding assays for S-2P and receptor-binding domain and neutralizing activity measured by PsVNA and PRNT (Figs. S3 through S7), which provides orthogonal support for each assay in characterizing the humoral response induced by mRNA-1273. I’m wondering how Oxford’s vaccine racks up compared to Moderna’s very good neutralizing antibody response. |
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#11592 |
Retired Hollywood Insider
Apr 2007
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#11593 | |
Blu-ray Jedi
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Glad to be back at work, hopefully it lasts, certainly is sooner than I expected. ![]() Last edited by Batman1980; 07-20-2020 at 07:13 PM. |
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#11594 | |
Blu-ray Archduke
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#11595 | |
Blu-ray Jedi
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#11597 | |
Blu-ray Duke
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The only good news is that NYS unemployment is extended from 23 weeks a year to 59. |
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#11598 |
Power Member
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Wow. The new deal for millions of new Covid-19 vaccine doses for the UK sounds like great news. I thought Italy or Spain could have got it done first if they were confident in getting them for their health service. But the only thing that I'm worried is how it works on the general population once they get it. The vaccine must be quite a reliable one to use if it become's suitable for mass usage.
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#11599 |
Retired Hollywood Insider
Apr 2007
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I’m limited with regards to the assay stuff in virology and much of the detail is beyond the scope of my knowledge. The way I see it is like in the movie American Sniper, neutralizing antibodies are similar to the Marines on the ground clearing out the enemy in the streets (the virus in your bloodstream, fluids, etc.), whereas T cells are like the other soldiers that have to bust open the door to enter a structure (the cells in your body) and then root out the enemy that has successfully moved from the streets into said building.
The value of the exact levels of each to best accomplish the mission is unknown, at least by me. Seems like Moderna’s vaccine may be stronger at clearing the streets and Oxford’s is stronger at house-to-house door kicking and virus killing. Nevertheless, the more encouraging vaccine candidates the better as I see them as shots on goal in soccer (football). And as Tony mentioned in that facebook interview on the last page, it’s good for all of us that companies and countries are willing to take the financial risk in order to expediate the process when none of these are sure shots. |
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#11600 |
Blu-ray Archduke
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80k dead and over 2 million infected in my country. Perhaps the most depressing thing of all is noticing how many people still aren't taking this seriously. Due to the carelessness, I believe we'll live with the damn virus for well over a year.
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Thanks given by: | shane01 (07-21-2020) |
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