Coronavirus (NO POLITICAL OR SOCIAL COMMENTARY PLEASE)

[jonmoz]

Originally Posted by MrHT

But that's why I'm frustrated. I'm more frustrated with humanity than the virus itself. The bolded part of your post are simple things requiring minimal effort and can work wonders in keeping the infection rate low. But people aren't doing it. Everyday I turn on the news and they announce, "Crowd gatherings today, no masks!" I'm like, really??? And the problem is, the infection rate has currently skyrocketed to the point where a vaccine could be useless at this point. But I hope I'm wrong.

Anyways, I apologize and had to vent that one last thing. I'll take a break starting now. Sorry for the trouble I may have caused and will refrain from posting here for a while.

No need to apologize for anything, you have the right to feel anyway you want to about this situation, and posting your feelings is not a crime, as long as you are civil about it, and from what I have read thus far your posts are fine.

[XavierTheaterPotato]

This pandemic is making me lose my god damn mind!

[veritas]

Originally Posted by Chaotic

lol. Masks arent 100% safe, just like seat belts. Many people who are trying their best not to catch it, are catching it.

If people are wearing good masks with p100 cartriges worn properly covering the whole face and they shave so the mask seals then the masks are pretty close to 100% effective. The problem is most people either arent wearing masks or they wear rather bad masks that offer very little protection for themselves and mostly protect others from them.

[R3P0]

FDA has approved the first treatment for COVID-19

Oct 22 (Reuters) - The U.S. Food and Drug Administration on Thursday approved Gilead Sciences Inc's remdesivir (Veklury). (Reporting by Vishwadha Chander in Bengaluru; Editing by Maju Samuel)

Source: https://www.cnn.com/2020/10/22/healt...-19/index.html

[Chaotic]

Colorado just Had it’s highest case count since the pandemic hit. Woo

[Leslie Dame]

Originally Posted by Steedeel

What about the hundreds of thousands of People who had to go into hospital and caught it in there?

Not denying this sin't happening, but I just spend five weeks at the hospital and caught nothing (was tested twice). Then again our area doesn't have much reported corona cases. I guess it all depents on location.

[Steedeel]

Originally Posted by Leslie Dame

Not denying this sin't happening, but I just spend five weeks at the hospital and caught nothing (was tested twice). Then again our area doesn't have much reported corona cases. I guess it all depents on location.

Yep, just take my tiny example. 2 family members positive, 38 people tested (obviously don’t know how strangers tests turned out) so all my family, people who had been in contact with us, people who had been in contact with first patient with COVID, staff etc..


Just one case in 1 day. Imagine that across the U.K., never mind the US and globe.

[Penton-Man]

Yesterday, the United States set a daily record for coronavirus cases as the number soared past 77,000, topping the previous high set in July. And with more cases comes more consequences, be it ‘long haulers’ or deaths.

[Penton-Man]

wise and important analysis -
there is “a golden mean” and at the 7:50 timestamp, Question - 'what one thing would be an improvement in federal response'? –

Dr. Fauci: Widespread Vaccine Distribution Likely 'Several Months Into 2021' | MTP Daily | MSNBC - YouTube

[atlantajoseph]

Originally Posted by veritas

If people are wearing good masks with p100 cartriges worn properly covering the whole face and they shave so the mask seals then the masks are pretty close to 100% effective. The problem is most people either arent wearing masks or they wear rather bad masks that offer very little protection for themselves and mostly protect others from them.

I don't shave but I do wear a cloth mask with filter. It may not be 100% effective but even if a small quantity of virus reached my mouth or nose, I would likely end up with a better outcome than if I'd gone maskless and received a much bigger viral load.

[Penton-Man]

Today, > 82,000 –

COVID-19 cases surge with more than 82,000 in single day - YouTube

among them, my brother-in-law - https://forum.blu-ray.com/showthread...o#post18159620
is hanging in there

[Anthony P]

Originally Posted by MrHT

So are you saying taking precautions doesn't work and that we should give up wearing masks and not social distance anymore???

No one is saying precautions should be abandoned because they are useless, nor that there not idiots out there.

Things could be much better if some people took more precautions and did not act like idiots.

- If someone goes for a test for covid-19, don't go around normally until the test comes back negative.
- there is no excuse for large gatherings. It boggles my mind when some ceremony (wedding, bar mitzvah, funeral, family reunion) hits the news because many people got infected because one person with covid attended
-people going to restaurants, bars, sporting events in places with cases
...

But the problem is when you act like every person that catches this is somehow deserving because they are idiots. At this point how it transmits is not fully known and sometimes things are out of peoples control. Like steed said, his sister needed surgery and caught it in the hospital getting that surgery. Also even if someone is an idiot and they could have easily avoided it, it does not mean that they don't have people that care for them that empathize with what the idiot is going through.

[Anthony P]

Originally Posted by veritas

If people are wearing good masks with p100 cartriges worn properly covering the whole face and they shave so the mask seals then the masks are pretty close to 100% effective. The problem is most people either arent wearing masks or they wear rather bad masks that offer very little protection for themselves and mostly protect others from them.

https://japantoday.com/category/nati...-not-perfectly

Scientists at the University of Tokyo built a secure chamber with mannequin heads facing each other. One head, fitted with a nebulizer, simulated coughing and expelled actual coronavirus particles. The other mimicked natural breathing, with a collection chamber for viruses coming through the airway.

A cotton mask reduced viral uptake by the receiver head by up to 40% compared to no mask. An N95 mask, used by medical professionals, blocked up to 90%. However, even when the N95 was fitted to the face with tape, some virus particles still sneaked in.

When a mask was attached to the coughing head, cotton and surgical masks blocked more than 50% of the virus transmission.

masks are a lot better than nothing especialy in the best of circumstances but they are not close to 100% even the best of them.

And this test assumes best case scenario (i.e. does the virus pass through the mask to reach the second persons respiratory system) directly, when it comes to reality there a lot more variables that make the effectiveness a lot less (like I said last week, waiting to pick up my groceries, I saw a lady come out of the store, immediately put he hands all over the mask to fold it up and then fix her makeup, if the mask did its job and stopped covid from making it to her, by her manipulation it was now all over her hands and then brought with her lipstick straight to her mouth where she would breath it in)

[JayTL]

So if cases are getting worse, but the government isn't doing anything about it..what does it matter?

Still have to go to work. Things will still be open.

[Anthony P]

either I missed it or it was deleted but did not see the following hews in here

https://www.bbc.com/news/health-54612293
UK plan to be first to run human challenge Covid trials

for those that don't know human challenge trials is where people are intentionally infected to test (in this case the effectiveness of one of the vaccines being developed there).

[veritas]

Originally Posted by JayTL

So if cases are getting worse, but the government isn't doing anything about it..what does it matter?

Still have to go to work. Things will still be open.

If the government does nothing then cases continue to go up exponentially until the market corrects on the consumers side. Once the hospitals are overwhelmed the death rate goes up and people panic again. eventually work shuts down either from lack of demand as people shop less or people quit because the risk of death or medical bills gets to high to justify what they are payed.

The problem with a correction on the consumer side is it will be slow. it takes 2 weeks before you really see peoples bad choices from covid in case numbers and death lag almost a month behind the true infection numbers (meaning the death rate looks like its going down before it goes up making stupid people do even more stupid things). That means a lot more people will die and your economy is still screwed in the long run.

The other problem is if you force the consumers to get scared and change habits the impact is long term. For example once people had decided theaters and airlines are not safe the recovery time frame was estimated to be years. If they let it explode and people have to fend for themselves then recovery will be much slower because of basically damaged consumer confidence.

[chip75]

Originally Posted by Anthony P

either I missed it or it was deleted but did not see the following hews in here

https://www.bbc.com/news/health-54612293
UK plan to be first to run human challenge Covid trials

for those that don't know human challenge trials is where people are intentionally infected to test (in this case the effectiveness of one of the vaccines being developed there).

One of the companies is advertising on Spotify.

[Penton-Man]

Originally Posted by Anthony P

either I missed it or it was deleted but did not see the following hews in here

https://www.bbc.com/news/health-54612293
UK plan to be first to run human challenge Covid trials

for those that don't know human challenge trials is where people are intentionally infected to test (in this case the effectiveness of one of the vaccines being developed there).

you must have missed it as it's several pages back - https://forum.blu-ray.com/showthread...y#post18216219

It’s a healthcare bioethical dilemma.
There is likely a tipping point in which HCT’s may become accepted as o.k. by most bioethicists, I’m just not quite sure if the U.K. is there yet in terms of the desperateness of the pandemic. One thing for certain is that volunteers should be lengthy counseled as to the seriousness of acquiring this virus and the fact that there is no cure for CIVID-19, perhaps even, when available, as part of the counseling, volunteers be given a tour thru an ICU with COVID-19 patients so they fully understand what they could be getting themselves into.

It would be interesting to hear Christine Grady’s (Dr. Fauci’s wife) position on this issue as she’s the head of the Department of Bioethics at the NIH.

[Anthony P]

Originally Posted by Penton-Man

you must have missed it as it's several pages back - https://forum.blu-ray.com/showthread...y#post18216219

It’s a healthcare bioethical dilemma.
There is likely a tipping point in which HCT’s may become accepted as o.k. by most bioethicists, I’m just not quite sure if the U.K. is there yet in terms of the desperateness of the pandemic. One thing for certain is that volunteers should be lengthy counseled as to the seriousness of acquiring this virus and the fact that there is no cure for CIVID-19, perhaps even, when available, as part of the counseling, volunteers be given a tour thru an ICU with COVID-19 patients so they fully understand what they could be getting themselves into.

It would be interesting to hear Christine Grady’s (Dr. Fauci’s wife) position on this issue as she’s the head of the Department of Bioethics at the NIH.

sorry rushed through the posts did not check out any video's.

I agree ethically it is a minefield. And honestly I don't know how I feel about it. Human challenges are great ways to get good answers, but let's be honest, it tends to prey on the vulnerable. I did not post it to open up that can of worms.

But in a time when there is very little even remotely good news I take it as the vaccine is far enough along and testing well that they think it is relatively safe to do human testing on the next level and if they do do it we might have good answers on the effective ness of the vaccine.

[dublinbluray108]

Pfizer is saying that their 2 dose Covid vaccine, once it's approved in the US & Europe, could be ready to go by the end of next month.

Ireland could get the first consignment of a Covid-19 vaccine by the end of this year, the Irish Independent has learned.

Paul Reid, managing director of Pfizer Ireland, believes there are strong signs that his company's experimental jab could be approved for emergency authorisation at the end of next month. It already has 100 million doses manufactured and ready to go if it gets the green light from regulatory agencies in the United States and Europe.

He told the Irish Independent that Pfizer and its German partner BioNTech are now in discussions with the European Commission to work out an advance purchase agreement which would see member states, including Ireland, get a share-out of the first deliveries.

"We can have 100 million doses by the end of 2020. If we have an advance purchase agreement with the EU Commission, that is secured. Part of that would include a volume we think we can make available across Europe."

The vaccine involves two doses and is being tested on 44,000 people of all ages.

"We are accelerating through the clinical trial programme at breakneck speed. We are seeing a speed of recruitment into the trials that we have never seen before. Already 40,000 have been recruited. We have over 35,000 participants who received the second dose of the vaccine."

A number of hurdles have to be crossed before it would be ready to administer to the public.

The first stage is to submit it for emergency use authorisation to the FDA in the United States early next month and the European Medicines Agency shortly afterwards.

"The FDA will review the data with their own scientists. It will be reviewed by an external panel of independent experts at a publicly held meeting," he said. As part of the fast-track approach the company has been submitting its data to the European licensing authority on a rolling basis since the *trials began.

Normally, this information is given at the end of clinical trials.

"Once it becomes available it is given to them for review," said Mr Reid, who added that safety is crucial.

"We are going to have to demonstrate the quality and consistency of the vaccine."

Mr Reid said the company had been investing since the early days of the pandemic to ensure its manufacturing processes were ready to meet the capacity demands needed to manufacture the levels of vaccine that would be commanded.

He revealed that the results were very promising.

"We are trying to be as open as possible. We are sharing any conclusive read-out data, whether positive or negative, within a few days after independent scientists see it.

"The positivity around the vaccine is predicated on good science so far."

One of the tests of any Covid vaccine will be its efficacy and how it performs across various age groups. The Pfizer candidate has been trialled in participants from age 12 years and upwards.

Staff in the Pfizer Grange Castle site in west Dublin have been involved in quality testing to support the manufacturing of the jab in Belgium.

The EU Commission, with funding from member states, has already entered into advance purchasing agreements with three other companies hoping to produce a successful vaccine - including experimental jabs from Oxford-AstraZeneca, Sanofi and Johnson & Johnson.

But it now looks like Pfizer is in pole position to be first past the finishing line.

If there are early batches of a successful vaccine transported here, the Government will decide who should get the injection first based on advice from its immunisation advisory group.

Frontline healthcare workers and at-risk groups such as nursing home residents would likely be first in the queue.

Mr Reid said the plan was to produce 1.3 billion doses next year. One of the challenges will be to produce the volume of vaccines required for such a global demand.

The initial roll-out of the vaccine will still mean that physical distancing and other Covid rules would have to be followed.

But with at-risk groups given some protection, depending on its efficacy, the need for lockdowns will recede.

https://www.independent.ie/irish-new...-39662915.html