Does setting the Sharpness to 0 affect HDTV

[KBMS]

Hi, I have a 46' Sharp Aquos, and in researching calibrating my TV and for watching Blu's I have read on the boards on setting the sharpness to low or 0 to lessen the grain affect in some movies that are either there due to director intent, or sporadic grain due to film typ and lens settings (a' la Enchanted that looks wonderful but some of the darker end scenes are grainy).

Anyways, I was wondering if setting the sharpness to 0 is beneficial for watching Blu's will it also have any benefit or adverse affect when watching reg tv or my HD channels

Thanks